- Universities can end up behaving like patent trolls, enforcing patent rights with no intention of working the invention. Some universities have been aggressive in enforcing their patent rights.
- Given that universities do not work the invention, they have no interest in cross-licensing and so can be more difficult to negotiate with.
- Academics feel pressurised to commercialise their work. It adds to their stress and this could cause long term damage to the culture of innovative research in universities.
- It could lead to a change in the areas which are researched, commercialisable research being favoured, so that certain important areas may get neglected as a result.
- The production of patents will be favoured over journal publications, which would be a loss to our collective knowledge.
- Ownership issues over patents could hinder cooperation and sharing of information between scientists.
- There is an argument that publically funded research should be available to all, and perhaps university research should be used to promote open innovation.
- There is a question as to whether commercialisation of research changes the role of universities in the research ecosystem. Their role changes from one of having social responsibility to one of generating profits.